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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TP1229 | β-Amyloid (1-15) | Amyloid β-Protein (1-15) | Beta Amyloid |
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease. | |||
TP1786L | Amyloid β-Protein 10-20 acetate | Amyloid β-Protein 10-20 acetate(152286-31-2 free base) | Beta Amyloid |
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α... | |||
T32106 | Human beta-amyloid protein 42 (1-7) | Vanutide | |
Human beta-amyloid protein 42 (1-7) is a bioactive chemical. | |||
TP1231 | β-Amyloid (29-40) | Amyloid beta-protein(29-40),β-Amyloid 29-40 | |
β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusio... | |||
T83540 | (Gly22)-amyloid beta-protein(1-40) | ||
Amyloid beta-protein(1-40) Arctic variant (Ab40ARC (E22G)), featuring a glycine at position 22 (Gly22), is a peptide utilized in Alzheimer's disease research [1]. | |||
TP1225 | β-Amyloid (22-35) | β-Amyloid 22-35,Amyloid β-Protein (22-35) | |
β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide. | |||
TP1228 | β-Amyloid (1-16) | Amyloid β-Protein (1-16),β-Amyloid 1-16 | |
β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is... | |||
TP1226 | β-Amyloid (1-28) | Amyloid β-Protein (1-28),β-Amyloid 1-28 | |
β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. | |||
TP1786 | β-Amyloid (10-20) | Amyloid β-Protein 10-20 | |
Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains ... | |||
TP1227 | β-Amyloid (12-28) | β-amyloid 12-28,Amyloid β-Protein (12-28) | |
Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo. | |||
TP2171 | β-amyloid (12-28) (TFA) (107015-83-8 free base) | Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA) | Others |
β-amyloid (12-28) TFA, a peptide fragment of β-amyloid protein (β1-42), is the major component of senile plaque cores. β-amyloid (12-28) has aggregation properties and the potential for Alzheimer’s disease research. | |||
TP1655 | β-Amyloid Protein Precursor 770 (135-155) | β-Amyloid Protein Precursor 770 135-155 | |
Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155) | |||
T80622 | Trontinemab | ||
Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC). It is utilized in research on Alzheimer's disease (AD) [1] [2]. | |||
T13253 | Umibecestat | CNP520 | BACE |
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of al... | |||
TP1719 | β-Amyloid (33-40) | β-Amyloid 33-40 | |
β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein. | |||
TP1586 | β-Amyloid (35-42) | β-Amyloid 35-42 | |
β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42. | |||
T3161 | β-Secretase inhibitor-STA | Beta-Secretase | |
BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor | |||
TP1692 | β-Amyloid (13-27) | β-Amyloid 13-27 | |
β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta a... | |||
TP1544 | β-Amyloid (22-40) | β-Amyloid 22-40 | |
This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein. This peptide sequence is often used in beta amyloid structure and aggregation studies. | |||
T76588 | (Asp37)-Amyloid β-Protein (1-42) | ||
'(Asp37)-Amyloid β-Protein (1-42) [1]' refers to the G37D mutant variant of the wild-type Amyloid-beta (1-42) peptide. | |||
TP1500 | β-Amyloid (1-17) | β-Amyloid 1-17 | |
This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies. | |||
T30879 | CHF-5022 | UNII-JO8EVV007Q,CHEMBL196246,CHF5022 | |
CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42). | |||
TP1538 | β-Amyloid (1-20) | β-Amyloid 1-20 | |
This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein. | |||
T83539 | (Pyr11)-Amyloid β-Protein (11-40) | ||
(Pyr11)-Amyloid β-Protein (11-40) (Aβ11pE-40), a peptide, is utilized in Alzheimer's disease research [1]. | |||
T83506 | [Asn23]-beta-Amyloid (1-42), iowa mutation | ||
[Asn23]-beta-Amyloid (1-42), Iowa mutation, is a biologically active peptide exhibiting increased aggregation propensity and fibril toxicity. This mutation involves the substitution of Aspartic acid (Asp) at position 23 ... | |||
T81299 | Remternetug | LY3372993 | |
Remternetug is a humanized IgG1-kappa monoclonal antibody that targets the N3pGlu peptide of the amyloid beta A4 precursor protein (APP) Aβ42. It specifically binds to the pyroglutamate-modified form of Aβ, which is impl... | |||
T35498 | β-Amyloid (1-14),mouse,rat | ||
β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-se... | |||
T83507 | [Asn23] β-Amyloid (1-40), Iowa mutation | ||
[Asn23] β-Amyloid (1-40), Iowa mutation, is a biologically active peptide associated with autosomal dominant Alzheimer's Disease in multiple families. This specific mutation involves the substitution of Asp 23 with Asn, ... | |||
T61206 | AChE/BChE/BACE-1-IN-1 | ||
AChE/BChE/BACE-1-IN-1 (Compound 4k) is an orally active inhibitor that targets acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It displays IC50 ... | |||
T82242 | HAChE-IN-6 | ||
hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM. It also demonstrates inhibitory effects on human butyrylcholinesterase (hBuChE) and glycogen synthase kin... | |||
T82243 | HAChE-IN-5 | GSK-3 | |
hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with IC50 values of 0.17 μM for both enzymes. Additionally, it de... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02221 | Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) | Human | E. coli |
Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.4 kDa and the accession number is P05067-1. | |||
TMPY-02110 | Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) | Human | E. coli |
Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 31.8 kDa and the accession number is P05067-1. | |||
TMPY-03885 | Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) | Human | E. coli |
Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.1 kDa and the accession number is P05067... | |||
TMPY-03884 | Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) | Human | E. coli |
Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.2 kDa and the accession number is P05067... | |||
TMPY-04693 | APLP1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
APLP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.4 kDa and the accession number is Q03157. | |||
TMPY-03628 | APLP1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
APLP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.9 kDa and the accession number is P51693-1. | |||
TMPY-00668 | APP/Protease nexin-II Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8. | |||
TMPJ-00338 | LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions u... | |||
TMPH-00929 | APBA2 Protein, Human, Recombinant (His & Myc) | Human | HEK293 Cells |
Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence fo... | |||
TMPH-00928 | APBA2 Protein, Human, Recombinant (E. coli, His & Myc) | Human | E. coli |
APBA2 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli. | |||
TMPJ-00722 | APBA3 Protein, Human, Recombinant (His) | Human | E. coli |
Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloi... | |||
TMPY-04396 | C-ABL/ABL1 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy... | |||
TMPH-03328 | Mcpt1 Protein, Rat, Recombinant (Myc) | Rat | E. coli |
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein wh... | |||
TMPJ-00782 | Amyloid Precursor Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and... | |||
TMPH-02778 | Mcpt4 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala... | |||
TMPK-00507 | TREM2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) w... | |||
TMPH-02106 | SH3PXD2A Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides... | |||
TMPY-03065 | BACE2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is th... | |||
TMPJ-01008 | THOP1 Protein, Human, Recombinant (His) | Human | E. coli |
Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detec... | |||
TMPH-01503 | Humanin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e... | |||
TMPY-01303 | Serpin A3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be... | |||
TMPH-01502 | Humanin Protein, Human, Recombinant (GST) | Human | E. coli |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e... | |||
TMPY-02063 | Alpha-2-macroglobulin Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
alpha-2-macroglobulin, also known as α2-macroglobulin (α2M and A2M), is an abundant protein of the plasma of vertebrates and members of several invertebrate phyla and functions as a broad-spectrum protease-binding protei... | |||
TMPH-02282 | Ubiquilin-1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS), autophagy and endoplasmic reticulum-associated protein degradation (ERAD) pa... |
カタログ番号 | 製品名 | ||
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L1310 | Cytoskeletal Signaling Pathway Compound Library | 759 compounds | |
A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS; |