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Search Results for " Amyloid beta-Protein "

ターゲット

31

阻害剤

24

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
TP1229 β-Amyloid (1-15) Amyloid β-Protein (1-15) Beta Amyloid
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.
TP1786L Amyloid β-Protein 10-20 acetate Amyloid β-Protein 10-20 acetate(152286-31-2 free base) Beta Amyloid
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α...
T32106 Human beta-amyloid protein 42 (1-7) Vanutide
Human beta-amyloid protein 42 (1-7) is a bioactive chemical.
TP1231 β-Amyloid (29-40) Amyloid beta-protein(29-40),β-Amyloid 29-40
β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusio...
T83540 (Gly22)-amyloid beta-protein(1-40)
Amyloid beta-protein(1-40) Arctic variant (Ab40ARC (E22G)), featuring a glycine at position 22 (Gly22), is a peptide utilized in Alzheimer's disease research [1].
TP1225 β-Amyloid (22-35) β-Amyloid 22-35,Amyloid β-Protein (22-35)
β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.
TP1228 β-Amyloid (1-16) Amyloid β-Protein (1-16),β-Amyloid 1-16
β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is...
TP1226 β-Amyloid (1-28) Amyloid β-Protein (1-28),β-Amyloid 1-28
β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.
TP1786 β-Amyloid (10-20) Amyloid β-Protein 10-20
Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains ...
TP1227 β-Amyloid (12-28) β-amyloid 12-28,Amyloid β-Protein (12-28)
Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo.
TP2171 β-amyloid (12-28) (TFA) (107015-83-8 free base) Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA) Others
β-amyloid (12-28) TFA, a peptide fragment of β-amyloid protein (β1-42), is the major component of senile plaque cores. β-amyloid (12-28) has aggregation properties and the potential for Alzheimer’s disease research.
TP1655 β-Amyloid Protein Precursor 770 (135-155) β-Amyloid Protein Precursor 770 135-155
Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)
T80622 Trontinemab
Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC). It is utilized in research on Alzheimer's disease (AD) [1] [2].
T13253 Umibecestat CNP520 BACE
Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of al...
TP1719 β-Amyloid (33-40) β-Amyloid 33-40
β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.
TP1586 β-Amyloid (35-42) β-Amyloid 35-42
β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.
T3161 β-Secretase inhibitor-STA Beta-Secretase
BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor
TP1692 β-Amyloid (13-27) β-Amyloid 13-27
β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta a...
TP1544 β-Amyloid (22-40) β-Amyloid 22-40
This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein. This peptide sequence is often used in beta amyloid structure and aggregation studies.
T76588 (Asp37)-Amyloid β-Protein (1-42)
'(Asp37)-Amyloid β-Protein (1-42) [1]' refers to the G37D mutant variant of the wild-type Amyloid-beta (1-42) peptide.
TP1500 β-Amyloid (1-17) β-Amyloid 1-17
This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
T30879 CHF-5022 UNII-JO8EVV007Q,CHEMBL196246,CHF5022
CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).
TP1538 β-Amyloid (1-20) β-Amyloid 1-20
This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.
T83539 (Pyr11)-Amyloid β-Protein (11-40)
(Pyr11)-Amyloid β-Protein (11-40) (Aβ11pE-40), a peptide, is utilized in Alzheimer's disease research [1].
T83506 [Asn23]-beta-Amyloid (1-42), iowa mutation
[Asn23]-beta-Amyloid (1-42), Iowa mutation, is a biologically active peptide exhibiting increased aggregation propensity and fibril toxicity. This mutation involves the substitution of Aspartic acid (Asp) at position 23 ...
T81299 Remternetug LY3372993
Remternetug is a humanized IgG1-kappa monoclonal antibody that targets the N3pGlu peptide of the amyloid beta A4 precursor protein (APP) Aβ42. It specifically binds to the pyroglutamate-modified form of Aβ, which is impl...
T35498 β-Amyloid (1-14),mouse,rat
β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-se...
T83507 [Asn23] β-Amyloid (1-40), Iowa mutation
[Asn23] β-Amyloid (1-40), Iowa mutation, is a biologically active peptide associated with autosomal dominant Alzheimer's Disease in multiple families. This specific mutation involves the substitution of Asp 23 with Asn, ...
T61206 AChE/BChE/BACE-1-IN-1
AChE/BChE/BACE-1-IN-1 (Compound 4k) is an orally active inhibitor that targets acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1). It displays IC50 ...
T82242 HAChE-IN-6
hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM. It also demonstrates inhibitory effects on human butyrylcholinesterase (hBuChE) and glycogen synthase kin...
T82243 HAChE-IN-5 GSK-3
hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with IC50 values of 0.17 μM for both enzymes. Additionally, it de...

Compounds

β-Amyloid (1-15)
TP1229
Synonym: Amyloid β-Protein (1-15)
Target: Beta Amyloid
Amyloid β-Protein 10-20 acetate
TP1786L
Synonym: Amyloid β-Protein 10-20 acetate(152286-31-2 free base)
Target: Beta Amyloid
Human beta-amyloid protein 42 (1-7)
T32106
Synonym: Vanutide
Target:
β-Amyloid (29-40)
TP1231
Synonym: Amyloid beta-protein(29-40),β-Amyloid 29-40
Target:
(Gly22)-amyloid beta-protein(1-40)
T83540
Synonym:
Target:
β-Amyloid (22-35)
TP1225
Synonym: β-Amyloid 22-35,Amyloid β-Protein (22-35)
Target:
β-Amyloid (1-16)
TP1228
Synonym: Amyloid β-Protein (1-16),β-Amyloid 1-16
Target:
β-Amyloid (1-28)
TP1226
Synonym: Amyloid β-Protein (1-28),β-Amyloid 1-28
Target:
β-Amyloid (10-20)
TP1786
Synonym: Amyloid β-Protein 10-20
Target:
β-Amyloid (12-28)
TP1227
Synonym: β-amyloid 12-28,Amyloid β-Protein (12-28)
Target:
β-amyloid (12-28) (TFA) (107015-83-8 free base)
TP2171
Synonym: Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA)
Target: Others
β-Amyloid Protein Precursor 770 (135-155)
TP1655
Synonym: β-Amyloid Protein Precursor 770 135-155
Target:
Trontinemab
T80622
Synonym:
Target:
Umibecestat
T13253
Synonym: CNP520
Target: BACE
β-Amyloid (33-40)
TP1719
Synonym: β-Amyloid 33-40
Target:
β-Amyloid (35-42)
TP1586
Synonym: β-Amyloid 35-42
Target:
β-Secretase inhibitor-STA
T3161
Synonym:
Target: Beta-Secretase
β-Amyloid (13-27)
TP1692
Synonym: β-Amyloid 13-27
Target:
β-Amyloid (22-40)
TP1544
Synonym: β-Amyloid 22-40
Target:
(Asp37)-Amyloid β-Protein (1-42)
T76588
Synonym:
Target:
β-Amyloid (1-17)
TP1500
Synonym: β-Amyloid 1-17
Target:
CHF-5022
T30879
Synonym: UNII-JO8EVV007Q,CHEMBL196246,CHF5022
Target:
β-Amyloid (1-20)
TP1538
Synonym: β-Amyloid 1-20
Target:
(Pyr11)-Amyloid β-Protein (11-40)
T83539
Synonym:
Target:
[Asn23]-beta-Amyloid (1-42), iowa mutation
T83506
Synonym:
Target:
Remternetug
T81299
Synonym: LY3372993
Target:
β-Amyloid (1-14),mouse,rat
T35498
Synonym:
Target:
[Asn23] β-Amyloid (1-40), Iowa mutation
T83507
Synonym:
Target:
AChE/BChE/BACE-1-IN-1
T61206
Synonym:
Target:
hAChE-IN-6
T82242
Synonym:
Target:
hAChE-IN-5
T82243
Synonym:
Target: GSK-3

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02221 Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) Human E. coli
Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.4 kDa and the accession number is P05067-1.
TMPY-02110 Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) Human E. coli
Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 31.8 kDa and the accession number is P05067-1.
TMPY-03885 Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) Human E. coli
Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.1 kDa and the accession number is P05067...
TMPY-03884 Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) Human E. coli
Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.2 kDa and the accession number is P05067...
TMPY-04693 APLP1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
APLP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.4 kDa and the accession number is Q03157.
TMPY-03628 APLP1 Protein, Human, Recombinant (His) Human HEK293 Cells
APLP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.9 kDa and the accession number is P51693-1.
TMPY-00668 APP/Protease nexin-II Protein, Human, Recombinant (hFc) Human HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPJ-00338 LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions u...
TMPH-00929 APBA2 Protein, Human, Recombinant (His & Myc) Human HEK293 Cells
Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence fo...
TMPH-00928 APBA2 Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
APBA2 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli.
TMPJ-00722 APBA3 Protein, Human, Recombinant (His) Human E. coli
Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloi...
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPH-03328 Mcpt1 Protein, Rat, Recombinant (Myc) Rat E. coli
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein wh...
TMPJ-00782 Amyloid Precursor Protein, Human, Recombinant (hFc) Human HEK293 Cells
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and...
TMPH-02778 Mcpt4 Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala...
TMPK-00507 TREM2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2  consists of a 156 amino acid (aa) extracellular domain (ECD) w...
TMPH-02106 SH3PXD2A Protein, Human, Recombinant (His & Myc) Human E. coli
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides...
TMPY-03065 BACE2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is th...
TMPJ-01008 THOP1 Protein, Human, Recombinant (His) Human E. coli
Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detec...
TMPH-01503 Humanin Protein, Human, Recombinant (hFc) Human HEK293 Cells
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e...
TMPY-01303 Serpin A3 Protein, Human, Recombinant (His) Human HEK293 Cells
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
TMPH-01502 Humanin Protein, Human, Recombinant (GST) Human E. coli
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e...
TMPY-02063 Alpha-2-macroglobulin Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
alpha-2-macroglobulin, also known as α2-macroglobulin (α2M and A2M), is an abundant protein of the plasma of vertebrates and members of several invertebrate phyla and functions as a broad-spectrum protease-binding protei...
TMPH-02282 Ubiquilin-1 Protein, Human, Recombinant (His & Myc) Human E. coli
Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS), autophagy and endoplasmic reticulum-associated protein degradation (ERAD) pa...
Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)
TMPY-02221
Species: Human
Expression System: E. coli
Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)
TMPY-02110
Species: Human
Expression System: E. coli
Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)
TMPY-03885
Species: Human
Expression System: E. coli
Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)
TMPY-03884
Species: Human
Expression System: E. coli
APLP1 Protein, Mouse, Recombinant (His)
TMPY-04693
Species: Mouse
Expression System: HEK293 Cells
APLP1 Protein, Human, Recombinant (His)
TMPY-03628
Species: Human
Expression System: HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc)
TMPY-00668
Species: Human
Expression System: HEK293 Cells
LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00338
Species: Human
Expression System: HEK293 Cells
APBA2 Protein, Human, Recombinant (His & Myc)
TMPH-00929
Species: Human
Expression System: HEK293 Cells
APBA2 Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-00928
Species: Human
Expression System: E. coli
APBA3 Protein, Human, Recombinant (His)
TMPJ-00722
Species: Human
Expression System: E. coli
C-ABL/ABL1 Protein, Human, Recombinant (GST)
TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
Mcpt1 Protein, Rat, Recombinant (Myc)
TMPH-03328
Species: Rat
Expression System: E. coli
Amyloid Precursor Protein, Human, Recombinant (hFc)
TMPJ-00782
Species: Human
Expression System: HEK293 Cells
Mcpt4 Protein, Mouse, Recombinant (E. coli, His)
TMPH-02778
Species: Mouse
Expression System: E. coli
TREM2 Protein, Cynomolgus, Recombinant (His)
TMPK-00507
Species: Cynomolgus
Expression System: HEK293 Cells
SH3PXD2A Protein, Human, Recombinant (His & Myc)
TMPH-02106
Species: Human
Expression System: E. coli
BACE2 Protein, Mouse, Recombinant (His)
TMPY-03065
Species: Mouse
Expression System: HEK293 Cells
THOP1 Protein, Human, Recombinant (His)
TMPJ-01008
Species: Human
Expression System: E. coli
Humanin Protein, Human, Recombinant (hFc)
TMPH-01503
Species: Human
Expression System: HEK293 Cells
Serpin A3 Protein, Human, Recombinant (His)
TMPY-01303
Species: Human
Expression System: HEK293 Cells
Humanin Protein, Human, Recombinant (GST)
TMPH-01502
Species: Human
Expression System: E. coli
Alpha-2-macroglobulin Protein, Human, Recombinant (His)
TMPY-02063
Species: Human
Expression System: Baculovirus Insect Cells
Ubiquilin-1 Protein, Human, Recombinant (His & Myc)
TMPH-02282
Species: Human
Expression System: E. coli
カタログ番号 製品名
L1310 Cytoskeletal Signaling Pathway Compound Library

759 compounds
A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS;